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Guilhermino and L

In recent years, an increasing number of people, especially the older population, have been drawn to such areas, including trekkers, climbers, miners, military personnel, astronomers, and athletes undergoing sports training

Gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal NLRP3-mediated neuroinflammation in a postpartum depression mouse model

These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism